
Hotels in Isle of Palms, Jacksonville
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Our top choices for Isle of Palms hotels

1. Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Residence Inn By Marriott Jacksonville - Mayo Clinic AreaIsle of Palms
9.4 out of 10, Exceptional, (617 reviews)
The price is CA $193
CA $219 total
includes taxes & fees
Nov 20 - Nov 21

2. Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic3 km from Isle of Palms
9.0 out of 10, Wonderful, (1,006 reviews)
The price is CA $181
CA $205 total
includes taxes & fees
Nov 15 - Nov 16

3. Holiday Inn Express Jacksonville Beach by IHG
Holiday Inn Express Jacksonville Beach by IHG3.3 km from Isle of Palms
9.2 out of 10, Wonderful, (1,003 reviews)
The price is CA $161
CA $183 total
includes taxes & fees
Nov 23 - Nov 24

4. Hilton Jacksonville at Mayo Clinic near Beaches
Hilton Jacksonville at Mayo Clinic near Beaches2.1 km from Isle of Palms
9.2 out of 10, Wonderful, (391 reviews)
The price is CA $229
CA $260 total
includes taxes & fees
Nov 21 - Nov 22

5. Best Western Oceanfront
Best Western OceanfrontOceanfront, 4.4 km from Isle of Palms
9.0 out of 10, Wonderful, (1,008 reviews)
The price is CA $172
CA $195 total
includes taxes & fees
Nov 11 - Nov 12

6. TownePlace Suites by Marriott Jacksonville East
TownePlace Suites by Marriott Jacksonville East3 km from Isle of Palms
9.2 out of 10, Wonderful, (669 reviews)
The price is CA $174
CA $197 total
includes taxes & fees
Nov 22 - Nov 23

7. Hyatt Place Jacksonville / St. Johns Town Center
Hyatt Place Jacksonville / St. Johns Town Center9.7 km from Isle of Palms
9.2 out of 10, Wonderful, (1,200 reviews)
The price is CA $157
CA $178 total
includes taxes & fees
Nov 22 - Nov 23

8. Holiday Inn Jacksonville E 295 Baymeadows by IHG
Holiday Inn Jacksonville E 295 Baymeadows by IHG9.8 km from Isle of Palms
8.6 out of 10, Excellent, (1,001 reviews)
The price is CA $124
CA $141 total
includes taxes & fees
Nov 15 - Nov 16

9. Fairfield Inn & Suites by Marriott Jacksonville Beach
Fairfield Inn & Suites by Marriott Jacksonville BeachOceanfront, 5 km from Isle of Palms
8.6 out of 10, Excellent, (1,005 reviews)
The price is CA $202
CA $229 total
includes taxes & fees
Nov 15 - Nov 16

10. Seahorse Oceanfront Inn
Seahorse Oceanfront Inn6.6 km from Isle of Palms
8.8 out of 10, Excellent, (855 reviews)
The price is CA $153
CA $206 total
includes taxes & fees
Nov 16 - Nov 17

11. Margaritaville Jacksonville Beach
Margaritaville Jacksonville BeachOceanfront, 4.6 km from Isle of Palms
8.8 out of 10, Excellent, (4,673 reviews)
The price is CA $208
CA $236 total
includes taxes & fees
Dec 3 - Dec 4

12. Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area3.7 km from Isle of Palms
9.0 out of 10, Wonderful, (1,252 reviews)
The price is CA $169
CA $192 total
includes taxes & fees
Nov 23 - Nov 24

13. Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG3.9 km from Isle of Palms
9.0 out of 10, Wonderful, (1,032 reviews)
The price is CA $155
CA $176 total
includes taxes & fees
Dec 6 - Dec 7

14. Hyatt Studios Jacksonville/St Johns Town Center
Hyatt Studios Jacksonville/St Johns Town Center8.9 km from Isle of Palms
9.4 out of 10, Exceptional, (250 reviews)
The price is CA $163
CA $185 total
includes taxes & fees
Nov 24 - Nov 25

15. Element by Marriott Jacksonville Beach
Element by Marriott Jacksonville BeachOceanfront, 4.2 km from Isle of Palms
9.6 out of 10, Exceptional, (597 reviews)
The price is CA $215
CA $244 total
includes taxes & fees
Nov 22 - Nov 23

16. Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass8.7 km from Isle of Palms
9.0 out of 10, Wonderful, (1,008 reviews)
The price is CA $179
CA $199 total
includes taxes & fees
Nov 16 - Nov 17

17. Tru By Hilton Jacksonville St Johns Town Center
Tru By Hilton Jacksonville St Johns Town Center9.7 km from Isle of Palms
9.2 out of 10, Wonderful, (986 reviews)
The price is CA $142
CA $161 total
includes taxes & fees
Nov 22 - Nov 23

18. Springhill Suites By Marriott Jacksonville Beach Oceanfront
Springhill Suites By Marriott Jacksonville Beach OceanfrontOceanfront, 4.5 km from Isle of Palms
9.0 out of 10, Wonderful, (818 reviews)
The price is CA $239
CA $271 total
includes taxes & fees
Nov 23 - Nov 24

19. Sheraton Jacksonville Hotel
Sheraton Jacksonville Hotel10.7 km from Isle of Palms
9.0 out of 10, Wonderful, (1,004 reviews)
The price is CA $154
CA $175 total
includes taxes & fees
Nov 23 - Nov 24

20. SpringHill Suites by Marriott Jacksonville
SpringHill Suites by Marriott Jacksonville12.1 km from Isle of Palms
8.6 out of 10, Excellent, (1,002 reviews)
The price is CA $148
CA $168 total
includes taxes & fees
Nov 15 - Nov 16
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels in Isle of Palms
Property | Star rating | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
![]() Residence Inn By Marriott Jacksonville - Mayo Clinic Area | 9.4 Exceptional 617 reviews | View | ||||||
![]() Holiday Inn Express Jacksonville Beach by IHG | 9.2 Wonderful 1,003 reviews | View | ||||||
![]() Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic | 9.0 Wonderful 1,006 reviews | View | ||||||
![]() Hilton Jacksonville at Mayo Clinic near Beaches | 9.2 Wonderful 391 reviews | View | ||||||
![]() TownePlace Suites by Marriott Jacksonville East | 9.2 Wonderful 669 reviews | View |
Where to stay in Isle of Palms
Find the best Isle of Palms areas and neighborhoods for the activities you enjoy most. Learn more about Isle of Palms
Learn more about Isle of Palms

Photo by Ryan Ketterman
Open Photo by Ryan Ketterman
Downtown Jacksonville
Historic core with major corporations, Downtown Jacksonville offers diverse culinary and nightlife experiences at The Elbow. Explore attractions like Florida Theatre, TIAA Bank Field, and museums, while enjoying convenient transportation options.

Amelia City
While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.

Oceanfront
If you're spending some time in Oceanfront, Oceanfront Park and Northeast Florida Beaches are top sights worth seeing.

Southside
If you're spending some time in Southside, St. Johns Town Center and Orange Park Place Shopping Center are top sights worth seeing.

Sawgrass
Visitors to Sawgrass like its beaches and riverfront, and Mickler Beach is a sight worth a stop.
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