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Hotels in Isle of Palms, Jacksonville

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Our top choices for Isle of Palms hotels

1. Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
Isle of Palms
9.4 out of 10, Exceptional, (617 reviews)
"Had a great experience while here. Rooms were clean and spacious. Will definitely stay here again."
United States
LISA
The price is CA $193
CA $219 total
includes taxes & fees
Nov 20 - Nov 21
Residence Inn By Marriott Jacksonville - Mayo Clinic Area

2. Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
2.5 star property
3 km from Isle of Palms
9.0 out of 10, Wonderful, (1,006 reviews)
"Loved the room, and the little cheese omelets at breakfast were good!"
United States
Kerry
The price is CA $181
CA $205 total
includes taxes & fees
Nov 15 - Nov 16
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic

3. Holiday Inn Express Jacksonville Beach by IHG

Holiday Inn Express Jacksonville Beach by IHG
3.0 star property
3.3 km from Isle of Palms
9.2 out of 10, Wonderful, (1,003 reviews)
"Great place to stay"
United States
Bobby
The price is CA $161
CA $183 total
includes taxes & fees
Nov 23 - Nov 24
Holiday Inn Express Jacksonville Beach by IHG

4. Hilton Jacksonville at Mayo Clinic near Beaches

Hilton Jacksonville at Mayo Clinic near Beaches
4.5 star property
2.1 km from Isle of Palms
9.2 out of 10, Wonderful, (391 reviews)
"A beautiful place will stay there again"
United States
Brandy
The price is CA $229
CA $260 total
includes taxes & fees
Nov 21 - Nov 22
Hilton Jacksonville at Mayo Clinic near Beaches

5. Best Western Oceanfront

Best Western Oceanfront
3.0 star property
Oceanfront, 4.4 km from Isle of Palms
9.0 out of 10, Wonderful, (1,008 reviews)
"Would stay again"
United States
Williams
The price is CA $172
CA $195 total
includes taxes & fees
Nov 11 - Nov 12
Best Western Oceanfront

6. TownePlace Suites by Marriott Jacksonville East

TownePlace Suites by Marriott Jacksonville East
3.0 star property
3 km from Isle of Palms
9.2 out of 10, Wonderful, (669 reviews)
"The room was very clean and comfortable. It would be nice to have the breakfast time last longer than 9:00am though."
United States
Lana
The price is CA $174
CA $197 total
includes taxes & fees
Nov 22 - Nov 23
TownePlace Suites by Marriott Jacksonville East

7. Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
3.0 star property
9.7 km from Isle of Palms
9.2 out of 10, Wonderful, (1,200 reviews)
"Clean rooms great location very nice"
United States
stephanie
The price is CA $157
CA $178 total
includes taxes & fees
Nov 22 - Nov 23
Hyatt Place Jacksonville / St. Johns Town Center

8. Holiday Inn Jacksonville E 295 Baymeadows by IHG

Holiday Inn Jacksonville E 295 Baymeadows by IHG
3.0 star property
9.8 km from Isle of Palms
8.6 out of 10, Excellent, (1,001 reviews)
"Great Hotel"
United States
Josh
The price is CA $124
CA $141 total
includes taxes & fees
Nov 15 - Nov 16
Holiday Inn Jacksonville E 295 Baymeadows by IHG

9. Fairfield Inn & Suites by Marriott Jacksonville Beach

Fairfield Inn & Suites by Marriott Jacksonville Beach
3.0 star property
Oceanfront, 5 km from Isle of Palms
8.6 out of 10, Excellent, (1,005 reviews)
"friendly and helpful staff. Breakfast was very good."
United States
Daniel
The price is CA $202
CA $229 total
includes taxes & fees
Nov 15 - Nov 16
Fairfield Inn & Suites by Marriott Jacksonville Beach

10. Seahorse Oceanfront Inn

Seahorse Oceanfront Inn
2.5 star property
6.6 km from Isle of Palms
8.8 out of 10, Excellent, (855 reviews)
"Great location, but we were sad the pool was closed for maintenance, if we had known that, we would've found somewhere else. Loved the location and being near everything."
United States
William
The price is CA $153
CA $206 total
includes taxes & fees
Nov 16 - Nov 17
Seahorse Oceanfront Inn

11. Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
Oceanfront, 4.6 km from Isle of Palms
8.8 out of 10, Excellent, (4,673 reviews)
"really enjoyed our stay"
United States
Lavorus
The price is CA $208
CA $236 total
includes taxes & fees
Dec 3 - Dec 4
Margaritaville Jacksonville Beach

12. Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
3.7 km from Isle of Palms
9.0 out of 10, Wonderful, (1,252 reviews)
"Excellent place to stay if spending time at Mayo"
United States
Jeffrey
The price is CA $169
CA $192 total
includes taxes & fees
Nov 23 - Nov 24
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

13. Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
3.9 km from Isle of Palms
9.0 out of 10, Wonderful, (1,032 reviews)
"Great stay"
United States
Alfredo
The price is CA $155
CA $176 total
includes taxes & fees
Dec 6 - Dec 7
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

14. Hyatt Studios Jacksonville/St Johns Town Center

Hyatt Studios Jacksonville/St Johns Town Center
2.5 star property
8.9 km from Isle of Palms
9.4 out of 10, Exceptional, (250 reviews)
"Terrific location and accommodations to match!"
United States
William
The price is CA $163
CA $185 total
includes taxes & fees
Nov 24 - Nov 25
Hyatt Studios Jacksonville/St Johns Town Center

15. Element by Marriott Jacksonville Beach

Element by Marriott Jacksonville Beach
3.0 star property
Oceanfront, 4.2 km from Isle of Palms
9.6 out of 10, Exceptional, (597 reviews)
"always a great stay. although this is our second time staying and something was broken in the bathroom."
United States
ariel
The price is CA $215
CA $244 total
includes taxes & fees
Nov 22 - Nov 23
Element by Marriott Jacksonville Beach

16. Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
3.0 star property
8.7 km from Isle of Palms
9.0 out of 10, Wonderful, (1,008 reviews)
"Great hotel and staff"
United States
Timothy
The price is CA $179
CA $199 total
includes taxes & fees
Nov 16 - Nov 17
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

17. Tru By Hilton Jacksonville St Johns Town Center

Tru By Hilton Jacksonville St Johns Town Center
2.5 star property
9.7 km from Isle of Palms
9.2 out of 10, Wonderful, (986 reviews)
"The staff was very welcoming,and friendly ."
United States
Janice
The price is CA $142
CA $161 total
includes taxes & fees
Nov 22 - Nov 23
Tru By Hilton Jacksonville St Johns Town Center

18. Springhill Suites By Marriott Jacksonville Beach Oceanfront

Springhill Suites By Marriott Jacksonville Beach Oceanfront
4.0 star property
Oceanfront, 4.5 km from Isle of Palms
9.0 out of 10, Wonderful, (818 reviews)
"great location"
United States
emily
The price is CA $239
CA $271 total
includes taxes & fees
Nov 23 - Nov 24
Springhill Suites By Marriott Jacksonville Beach Oceanfront

19. Sheraton Jacksonville Hotel

Sheraton Jacksonville Hotel
4.0 star property
10.7 km from Isle of Palms
9.0 out of 10, Wonderful, (1,004 reviews)
"Staff was real nice rooms were clean. Bartender was real nice facilities looked amazing."
United States
Jarvon
The price is CA $154
CA $175 total
includes taxes & fees
Nov 23 - Nov 24
Sheraton Jacksonville Hotel

20. SpringHill Suites by Marriott Jacksonville

SpringHill Suites by Marriott Jacksonville
3.0 star property
12.1 km from Isle of Palms
8.6 out of 10, Excellent, (1,002 reviews)
"Great staff!"
United States
Ashley
The price is CA $148
CA $168 total
includes taxes & fees
Nov 15 - Nov 16
SpringHill Suites by Marriott Jacksonville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Isle of Palms

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A spacious living area with a high ceiling, a fireplace, and a bar area in the background.
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
9.4
Exceptional
617 reviews
View
A modern lobby with seating areas, a flat-screen TV, and a coffee bar.
Holiday Inn Express Jacksonville Beach by IHG
3.0 star property
9.2
Wonderful
1,003 reviews
View
A hotel lobby with a bar area, seating arrangements, and a reception desk.
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
2.5 star property
9.0
Wonderful
1,006 reviews
View
A modern lobby with a central seating area, wooden shelving with decorative items, and a large pillar.
Hilton Jacksonville at Mayo Clinic near Beaches
4.5 star property
9.2
Wonderful
391 reviews
View
An outdoor seating area with a fire pit, wicker furniture, and a covered patio.
TownePlace Suites by Marriott Jacksonville East
3.0 star property
9.2
Wonderful
669 reviews
View

Where to stay in Isle of Palms

Find the best Isle of Palms areas and neighborhoods for the activities you enjoy most. Learn more about Isle of Palms
Learn more about Isle of Palms

Downtown Jacksonville

Historic core with major corporations, Downtown Jacksonville offers diverse culinary and nightlife experiences at The Elbow. Explore attractions like Florida Theatre, TIAA Bank Field, and museums, while enjoying convenient transportation options.

Amelia City

While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.

Oceanfront

If you're spending some time in Oceanfront, Oceanfront Park and Northeast Florida Beaches are top sights worth seeing.

Southside

If you're spending some time in Southside, St. Johns Town Center and Orange Park Place Shopping Center are top sights worth seeing.

Sawgrass

Visitors to Sawgrass like its beaches and riverfront, and Mickler Beach is a sight worth a stop.

Top Isle of Palms Hotel Reviews

Frequently asked questions

What are the best hotels in Isle Of Palms that travellers recommend?
For highly recommended hotels near the Mayo Clinic in Florida, consider the 3-star Residence Inn By Marriott Jacksonville - Mayo Clinic Area, the Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic, the 3-star Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches, the 3-star Holiday Inn Express Jacksonville Beach by IHG, and the 3-star TownePlace Suites by Marriott Jacksonville East.

The 3-star Residence Inn By Marriott Jacksonville - Mayo Clinic Area, with an excellent 9.4 rating, is located just 1.1 km from Mayo Clinic Florida. Guests frequently praise the beautiful and clean rooms, the exceptional staff, and the good and exceptional food, including a free buffet and continental breakfast. The hotel also features a poolside bar and air conditioning.

The Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic, rated 9.0, offers comfortable suites with Egyptian cotton sheets and premium bedding. Travellers appreciate the excellent and helpful staff, delicious breakfast, and nice and clean rooms. It also provides an indoor pool, fitness facilities, and accessible fitness areas.

The 3-star Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches, with a rating of 8.4, is exceptionally close to Mayo Clinic Florida, just 0.3 km away. Guests highlight the excellent location and helpful front desk staff, as well as good breakfast options. The hotel provides premium bedding, an outdoor pool, accessible fitness facilities, and free self-parking with electric car charging stations.

The 3-star Holiday Inn Express Jacksonville Beach by IHG, rated 9.2, is a great option for those who want to be near the beach. It is 1.4 km from Oceanfront Park and 1.2 km from Jacksonville Beach Pier. Guests praise the friendly and helpful staff, spacious and clean rooms, convenient location, and great breakfast. The hotel offers free buffet breakfast, free self-parking, and electric car charging stations.

Finally, the 3-star TownePlace Suites by Marriott Jacksonville East, with a 9.2 rating, is praised for its helpful and great staff, clean and great rooms, and great breakfast. It features air conditioning, free continental breakfast, and free self-parking with accessible parking and electric car charging stations. Guests also enjoy the nice fire pit.
What are the best family hotels in Isle Of Palms?
For excellent family-friendly hotels near Isle of Palms, consider the Holiday Inn Express Jacksonville Beach by IHG, the Residence Inn By Marriott Jacksonville - Mayo Clinic Area, and the TownePlace Suites by Marriott Jacksonville East.

The 3-star Holiday Inn Express Jacksonville Beach by IHG, with a 9.2 rating, offers convenient amenities such as connecting rooms, sofa beds, and free cribs, making it ideal for families. Guests appreciate the free internet, free self-parking, and complimentary buffet breakfast. It is also well-located, being just 1.1 km from Adventure Landing and 1.2 km from Jacksonville Beach Pier.

Another fantastic option is the 3-star Residence Inn By Marriott Jacksonville - Mayo Clinic Area, which boasts an outstanding 9.4 rating. This hotel provides child-friendly window designs, connecting rooms, and free rollaway extra beds, catering perfectly to families. A pool and complimentary buffet breakfast are also available.

The 3-star TownePlace Suites by Marriott Jacksonville East, rated 9.2, is also a great choice for families. It offers free cribs, sofa beds, a pool, and complimentary breakfast, including continental options. Guests frequently mention the helpful staff and clean rooms.
What hotels in Isle Of Palms offer free breakfast?
For hotels in Isle of Palms that offer free breakfast, consider the Residence Inn By Marriott Jacksonville - Mayo Clinic Area, the Holiday Inn Express Jacksonville Beach by IHG, the TownePlace Suites by Marriott Jacksonville East, and the Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic.

The 3-star Residence Inn By Marriott Jacksonville - Mayo Clinic Area, with an excellent 9.4 rating, provides a complimentary buffet breakfast with a good selection, ensuring a great start to your day. Guests also frequently mention the beautiful and clean rooms, as well as the exceptional staff.

Another fantastic option is the 3-star Holiday Inn Express Jacksonville Beach by IHG, rated 9.2. This hotel offers a free daily buffet breakfast, which guests consistently describe as great. Its convenient location places it within easy reach of Oceanfront Park, Jacksonville Beach Pier, and Gonzales Park.

The 3-star TownePlace Suites by Marriott Jacksonville East, with a 9.2 rating, also includes a complimentary continental breakfast daily. Guests appreciate the helpful staff and the clean, great rooms, with some enjoying the nice fire pit.

Finally, the Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic, rated 9.0, offers a free daily buffet breakfast that guests frequently describe as delicious. The staff are often highlighted as excellent and helpful, and the rooms are noted for being nice and clean.
What are the top pet-friendly hotels in Isle Of Palms?
For top pet-friendly hotels in Isle Of Palms, consider the Residence Inn By Marriott Jacksonville - Mayo Clinic Area, Holiday Inn Express Jacksonville Beach by IHG, Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic, and TownePlace Suites by Marriott Jacksonville East.

The 3-star Residence Inn By Marriott Jacksonville - Mayo Clinic Area, with an excellent 9.4 rating, warmly welcomes both dogs and cats. Guests frequently praise the beautiful and clean rooms, as well as the exceptional staff and food, especially the complimentary buffet breakfast.

Another great option is the 3-star Holiday Inn Express Jacksonville Beach by IHG, rated 9.2. This hotel also permits dogs and cats and offers a range of complimentary amenities including free internet, free self-parking, and a free buffet breakfast. Its convenient location is noted by guests, being just 1.4 km from Oceanfront Park and 1.2 km from Jacksonville Beach Pier.

The Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic, with a 9.0 rating, is another highly-rated pet-friendly choice. It permits dogs and cats and provides a delicious complimentary buffet breakfast and free WiFi. Guests appreciate the excellent and helpful staff, as well as the clean rooms and convenient location.

Finally, the 3-star TownePlace Suites by Marriott Jacksonville East, rated 9.2, is also pet-friendly and offers a complimentary continental breakfast and free WiFi. Guests often highlight the helpful staff and clean rooms, as well as the nice fire pit area.
What are the best budget hotels in Isle Of Palms?
For budget-friendly accommodation in Isle Of Palms, the Holiday Inn Express Jacksonville Beach by IHG, the Residence Inn By Marriott Jacksonville - Mayo Clinic Area, and the TownePlace Suites by Marriott Jacksonville East are highly recommended.

The 3-star Holiday Inn Express Jacksonville Beach by IHG, with a 9.2 rating, is praised by guests for its friendly and helpful staff, as well as its spacious and clean rooms. It offers complimentary breakfast, free WiFi, and free parking. The hotel is conveniently located near Oceanfront Park and Jacksonville Beach Pier, both within 1.4 km.

Another excellent option is the 3-star Residence Inn By Marriott Jacksonville - Mayo Clinic Area, which boasts an impressive 9.4 rating. Guests frequently praise its beautiful and clean rooms, along with exceptional staff and good breakfast options. The hotel provides free continental breakfast, free WiFi, and free self-parking.

The 3-star TownePlace Suites by Marriott Jacksonville East, rated 9.2, is also a great choice. Guests appreciate the helpful staff, clean rooms, and a great breakfast. This hotel offers complimentary continental breakfast, free WiFi, and free self-parking.
What are the best hotels in Isle Of Palms near Northeast Florida Beaches?
For hotels in Isle Of Palms near Northeast Florida Beaches, the Holiday Inn Express Jacksonville Beach by IHG comes highly recommended.

This 3-star hotel, with an excellent 9.2 rating, is particularly suitable for families due to amenities like connecting rooms, sofa beds, and free cribs. Guests consistently praise the friendly and helpful staff, the spacious and clean rooms, and the convenient location. You will also find a pool, free internet access, and a complimentary buffet breakfast. It is well-situated, being only 0.2 km from Gonzales Park, 0.8 km from Beaches Museum & History Park, and 1.2 km from Jacksonville Beach Pier.
Can I cancel my hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Isle of Palms hotel for you.
How much is the nightly rate at a Isle of Palms hotel?
Hotel prices in Isle of Palms often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

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