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Hotels in Isle of Palms, Jacksonville

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Our top choices for Isle of Palms hotels

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
Isle of Palms
9.4 out of 10, Exceptional, (542 reviews)
"My family stayed here. Clean hotel and great breakfast."
United States
Ryan
The price is CA $231
CA $262 total
includes taxes & fees
Jul 4 - Jul 5
Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Extended Stay America Premier Suites - Jacksonville - Airport

Extended Stay America Premier Suites - Jacksonville - Airport
2.5 star property
30.8 km from Isle of Palms
9.0 out of 10, Wonderful, (484 reviews)
"Excellent stay!"
United States
Amy
The price is CA $115
CA $130 total
includes taxes & fees
Jun 27 - Jun 28
Extended Stay America Premier Suites - Jacksonville - Airport

AC Hotel Jacksonville St Johns Town Center

AC Hotel Jacksonville St Johns Town Center
2.5 star property
9.1 km from Isle of Palms
9.4 out of 10, Exceptional, (210 reviews)
"Loved our stay"
United States
Jaime
The price is CA $215
CA $244 total
includes taxes & fees
Jun 26 - Jun 27
AC Hotel Jacksonville St Johns Town Center

La Quinta Inn & Suites by Wyndham Jacksonville Mandarin

La Quinta Inn & Suites by Wyndham Jacksonville Mandarin
3.0 star property
21.3 km from Isle of Palms
7.6 out of 10, Good, (525 reviews)
"The hotel was clean and staff was proficient."
United States
Maxine
The price is CA $103
CA $117 total
includes taxes & fees
Jun 25 - Jun 26
La Quinta Inn & Suites by Wyndham Jacksonville Mandarin

TownePlace Suites by Marriott® Jacksonville Mayport

TownePlace Suites by Marriott® Jacksonville Mayport
3.0 star property
9.7 km from Isle of Palms
9.6 out of 10, Exceptional, (111 reviews)
The price is CA $211
CA $239 total
includes taxes & fees
Jun 22 - Jun 23
TownePlace Suites by Marriott® Jacksonville Mayport

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
Oceanfront, 4.6 km from Isle of Palms
9.0 out of 10, Wonderful, (4,056 reviews)
"Great room and very convenient location"
United States
Lyndi
The price is CA $237
CA $269 total
includes taxes & fees
Jun 24 - Jun 25
Margaritaville Jacksonville Beach

Home2 Suites By Hilton Jacksonville Downtown

Home2 Suites By Hilton Jacksonville Downtown
3.0 star property
24.4 km from Isle of Palms
9.2 out of 10, Wonderful, (354 reviews)
"really enjoyed my stay at the hotel"
United States
Stacy
The price is CA $173
CA $196 total
includes taxes & fees
Jul 5 - Jul 6
Home2 Suites By Hilton Jacksonville Downtown

Seahorse Oceanfront Inn

Seahorse Oceanfront Inn
2.5 star property
6.6 km from Isle of Palms
8.8 out of 10, Excellent, (718 reviews)
"We liked the hotel, it was a nice experience. We all had a good time."
United States
Shannon
The price is CA $182
CA $239 total
includes taxes & fees
Jun 28 - Jun 29
Seahorse Oceanfront Inn

Holiday Inn Express Jacksonville - Blount Island by IHG

Holiday Inn Express Jacksonville - Blount Island by IHG
2.5 star property
20.3 km from Isle of Palms
8.8 out of 10, Excellent, (1,002 reviews)
"Nice staff and very clean"
United States
Amber
The price is CA $139
CA $157 total
includes taxes & fees
Jun 28 - Jun 29
Holiday Inn Express Jacksonville - Blount Island by IHG

Hilton Jacksonville At Mayo Clinic

Hilton Jacksonville At Mayo Clinic
4.5 star property
2.1 km from Isle of Palms
9.4 out of 10, Exceptional, (260 reviews)
"Great hotel and very convenient to Mayo."
United States
Margaret
The price is CA $243
CA $275 total
includes taxes & fees
Jul 12 - Jul 13
Hilton Jacksonville At Mayo Clinic

Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
3.0 star property
9.7 km from Isle of Palms
9.2 out of 10, Wonderful, (1,058 reviews)
"Location was very convenient"
United States
Thomas
The price is CA $180
CA $204 total
includes taxes & fees
Jun 25 - Jun 26
Hyatt Place Jacksonville / St. Johns Town Center

Courtyard by Marriott Jacksonville Beach Oceanfront

Courtyard by Marriott Jacksonville Beach Oceanfront
3.0 star property
Oceanfront, 5 km from Isle of Palms
8.6 out of 10, Excellent, (1,004 reviews)
"Great location, great staff."
United States
Donna
The price is CA $296
CA $336 total
includes taxes & fees
Jun 30 - Jul 1
Courtyard by Marriott Jacksonville Beach Oceanfront

Hampton Inn Jacksonville East Regency Square

Hampton Inn Jacksonville East Regency Square
2.5 star property
13 km from Isle of Palms
8.8 out of 10, Excellent, (1,003 reviews)
"The highlight of our trip to Jacksonville was the hotel where we stayed. The hotel staff—always smiling, helpful, and exemplifying true hospitality—along with the cleanliness of the hotel and the quality of the delicious, varied breakfast, left a lasting impression on us."
United States
Mehmet
The price is CA $116
CA $132 total
includes taxes & fees
Jul 18 - Jul 19
Hampton Inn Jacksonville East Regency Square

Wingate by Wyndham Jacksonville FL

Wingate by Wyndham Jacksonville FL
3.0 star property
15.4 km from Isle of Palms
7.4 out of 10, Good, (1,002 reviews)
"Clean room great staff always were helpful nice breakfast excellent housekeepers"
United States
Steven
The price is CA $96
CA $108 total
includes taxes & fees
Jun 22 - Jun 23
Wingate by Wyndham Jacksonville FL

Hyatt Studios Jacksonville/St Johns Town Center

Hyatt Studios Jacksonville/St Johns Town Center
2.5 star property
8.9 km from Isle of Palms
9.6 out of 10, Exceptional, (91 reviews)
"I really like this location and would definitely stay here again."
United States
Althia
The price is CA $191
CA $217 total
includes taxes & fees
Jul 5 - Jul 6
Hyatt Studios Jacksonville/St Johns Town Center

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
3.0 star property
8.7 km from Isle of Palms
9.0 out of 10, Wonderful, (1,001 reviews)
"Very enjoyable stay!"
United States
Kristin
The price is CA $180
CA $201 total
includes taxes & fees
Jul 5 - Jul 6
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

San Marco Inn East

San Marco Inn East
3.0 star property
19.7 km from Isle of Palms
8.6 out of 10, Excellent, (1,418 reviews)
"Excellent stay"
United States
shawn
The price is CA $84
CA $95 total
includes taxes & fees
Jun 22 - Jun 23
San Marco Inn East

Wyndham Garden Jacksonville

Wyndham Garden Jacksonville
3.0 star property
15.5 km from Isle of Palms
8.0 out of 10, Very good, (1,915 reviews)
"I enjoyed the stay"
United States
Siddiq
The price is CA $111
CA $126 total
includes taxes & fees
Jul 5 - Jul 6
Wyndham Garden Jacksonville

Quality Inn Atlantic Beach - Mayo Clinic Jax Area

Quality Inn Atlantic Beach - Mayo Clinic Jax Area
2.5 star property
9 km from Isle of Palms
7.8 out of 10, Good, (1,002 reviews)
"The room was clean. For the price I would stay here again."
United States
Karyn
The price is CA $144
CA $164 total
includes taxes & fees
Jun 29 - Jun 30
Quality Inn Atlantic Beach - Mayo Clinic Jax Area

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG

Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
2.5 star property
3.9 km from Isle of Palms
9.0 out of 10, Wonderful, (1,001 reviews)
"Everyone was very nice and the rooms were clean."
United States
Camille
The price is CA $180
CA $204 total
includes taxes & fees
Jun 28 - Jun 29
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Isle of Palms

Find the best Isle of Palms areas and neighborhoods for the activities you enjoy most. Learn more about Isle of Palms
Learn more about Isle of Palms

Amelia City

While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.

Downtown Jacksonville

Historic core with major corporations, Downtown Jacksonville offers diverse culinary and nightlife experiences at The Elbow. Explore attractions like Florida Theatre, TIAA Bank Field, and museums, while enjoying convenient transportation options.

Oceanfront

If you're spending some time in Oceanfront, Oceanfront Park and Northeast Florida Beaches are top sights worth seeing.

American Beach

If you're spending some time in American Beach, American Beach and Spanish Quarter Village are top sights worth seeing.

Sawgrass

Visitors to Sawgrass like its beaches and riverfront, and Mickler Beach is a sight worth a stop.

Top Isle of Palms Hotel Reviews

Frequently asked questions

What are the best hotels in Isle Of Palms that travellers recommend?
For highly recommended hotels near the Mayo Clinic in Florida, consider the 3-star Residence Inn By Marriott Jacksonville - Mayo Clinic Area, the Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic, the 3-star Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches, the 3-star Holiday Inn Express Jacksonville Beach by IHG, and the 3-star TownePlace Suites by Marriott Jacksonville East.

The 3-star Residence Inn By Marriott Jacksonville - Mayo Clinic Area, with an excellent 9.4 rating, is located just 1.1 km from Mayo Clinic Florida. Guests frequently praise the beautiful and clean rooms, the exceptional staff, and the good and exceptional food, including a free buffet and continental breakfast. The hotel also features a poolside bar and air conditioning.

The Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic, rated 9.0, offers comfortable suites with Egyptian cotton sheets and premium bedding. Travellers appreciate the excellent and helpful staff, delicious breakfast, and nice and clean rooms. It also provides an indoor pool, fitness facilities, and accessible fitness areas.

The 3-star Courtyard by Marriott Jacksonville at Mayo Clinic Campus/Beaches, with a rating of 8.4, is exceptionally close to Mayo Clinic Florida, just 0.3 km away. Guests highlight the excellent location and helpful front desk staff, as well as good breakfast options. The hotel provides premium bedding, an outdoor pool, accessible fitness facilities, and free self-parking with electric car charging stations.

The 3-star Holiday Inn Express Jacksonville Beach by IHG, rated 9.2, is a great option for those who want to be near the beach. It is 1.4 km from Oceanfront Park and 1.2 km from Jacksonville Beach Pier. Guests praise the friendly and helpful staff, spacious and clean rooms, convenient location, and great breakfast. The hotel offers free buffet breakfast, free self-parking, and electric car charging stations.

Finally, the 3-star TownePlace Suites by Marriott Jacksonville East, with a 9.2 rating, is praised for its helpful and great staff, clean and great rooms, and great breakfast. It features air conditioning, free continental breakfast, and free self-parking with accessible parking and electric car charging stations. Guests also enjoy the nice fire pit.
What are the best family hotels in Isle Of Palms?
For excellent family-friendly hotels near Isle of Palms, consider the Holiday Inn Express Jacksonville Beach by IHG, the Residence Inn By Marriott Jacksonville - Mayo Clinic Area, and the TownePlace Suites by Marriott Jacksonville East.

The 3-star Holiday Inn Express Jacksonville Beach by IHG, with a 9.2 rating, offers convenient amenities such as connecting rooms, sofa beds, and free cribs, making it ideal for families. Guests appreciate the free internet, free self-parking, and complimentary buffet breakfast. It is also well-located, being just 1.1 km from Adventure Landing and 1.2 km from Jacksonville Beach Pier.

Another fantastic option is the 3-star Residence Inn By Marriott Jacksonville - Mayo Clinic Area, which boasts an outstanding 9.4 rating. This hotel provides child-friendly window designs, connecting rooms, and free rollaway extra beds, catering perfectly to families. A pool and complimentary buffet breakfast are also available.

The 3-star TownePlace Suites by Marriott Jacksonville East, rated 9.2, is also a great choice for families. It offers free cribs, sofa beds, a pool, and complimentary breakfast, including continental options. Guests frequently mention the helpful staff and clean rooms.
What hotels in Isle Of Palms offer free breakfast?
For hotels in Isle of Palms that offer free breakfast, consider the Residence Inn By Marriott Jacksonville - Mayo Clinic Area, the Holiday Inn Express Jacksonville Beach by IHG, the TownePlace Suites by Marriott Jacksonville East, and the Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic.

The 3-star Residence Inn By Marriott Jacksonville - Mayo Clinic Area, with an excellent 9.4 rating, provides a complimentary buffet breakfast with a good selection, ensuring a great start to your day. Guests also frequently mention the beautiful and clean rooms, as well as the exceptional staff.

Another fantastic option is the 3-star Holiday Inn Express Jacksonville Beach by IHG, rated 9.2. This hotel offers a free daily buffet breakfast, which guests consistently describe as great. Its convenient location places it within easy reach of Oceanfront Park, Jacksonville Beach Pier, and Gonzales Park.

The 3-star TownePlace Suites by Marriott Jacksonville East, with a 9.2 rating, also includes a complimentary continental breakfast daily. Guests appreciate the helpful staff and the clean, great rooms, with some enjoying the nice fire pit.

Finally, the Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic, rated 9.0, offers a free daily buffet breakfast that guests frequently describe as delicious. The staff are often highlighted as excellent and helpful, and the rooms are noted for being nice and clean.
What are the top pet-friendly hotels in Isle Of Palms?
For top pet-friendly hotels in Isle Of Palms, consider the Residence Inn By Marriott Jacksonville - Mayo Clinic Area, Holiday Inn Express Jacksonville Beach by IHG, Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic, and TownePlace Suites by Marriott Jacksonville East.

The 3-star Residence Inn By Marriott Jacksonville - Mayo Clinic Area, with an excellent 9.4 rating, warmly welcomes both dogs and cats. Guests frequently praise the beautiful and clean rooms, as well as the exceptional staff and food, especially the complimentary buffet breakfast.

Another great option is the 3-star Holiday Inn Express Jacksonville Beach by IHG, rated 9.2. This hotel also permits dogs and cats and offers a range of complimentary amenities including free internet, free self-parking, and a free buffet breakfast. Its convenient location is noted by guests, being just 1.4 km from Oceanfront Park and 1.2 km from Jacksonville Beach Pier.

The Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic, with a 9.0 rating, is another highly-rated pet-friendly choice. It permits dogs and cats and provides a delicious complimentary buffet breakfast and free WiFi. Guests appreciate the excellent and helpful staff, as well as the clean rooms and convenient location.

Finally, the 3-star TownePlace Suites by Marriott Jacksonville East, rated 9.2, is also pet-friendly and offers a complimentary continental breakfast and free WiFi. Guests often highlight the helpful staff and clean rooms, as well as the nice fire pit area.
What are the best budget hotels in Isle Of Palms?
For budget-friendly accommodation in Isle Of Palms, the Holiday Inn Express Jacksonville Beach by IHG, the Residence Inn By Marriott Jacksonville - Mayo Clinic Area, and the TownePlace Suites by Marriott Jacksonville East are highly recommended.

The 3-star Holiday Inn Express Jacksonville Beach by IHG, with a 9.2 rating, is praised by guests for its friendly and helpful staff, as well as its spacious and clean rooms. It offers complimentary breakfast, free WiFi, and free parking. The hotel is conveniently located near Oceanfront Park and Jacksonville Beach Pier, both within 1.4 km.

Another excellent option is the 3-star Residence Inn By Marriott Jacksonville - Mayo Clinic Area, which boasts an impressive 9.4 rating. Guests frequently praise its beautiful and clean rooms, along with exceptional staff and good breakfast options. The hotel provides free continental breakfast, free WiFi, and free self-parking.

The 3-star TownePlace Suites by Marriott Jacksonville East, rated 9.2, is also a great choice. Guests appreciate the helpful staff, clean rooms, and a great breakfast. This hotel offers complimentary continental breakfast, free WiFi, and free self-parking.
What are the best hotels in Isle Of Palms near Northeast Florida Beaches?
For hotels in Isle Of Palms near Northeast Florida Beaches, the Holiday Inn Express Jacksonville Beach by IHG comes highly recommended.

This 3-star hotel, with an excellent 9.2 rating, is particularly suitable for families due to amenities like connecting rooms, sofa beds, and free cribs. Guests consistently praise the friendly and helpful staff, the spacious and clean rooms, and the convenient location. You will also find a pool, free internet access, and a complimentary buffet breakfast. It is well-situated, being only 0.2 km from Gonzales Park, 0.8 km from Beaches Museum & History Park, and 1.2 km from Jacksonville Beach Pier.
Can I cancel my hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline – this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Isle of Palms hotel for you.
How can I save on a Isle of Palms hotel booking with Expedia?
With Expedia, you'll unlock our lowest prices by becoming a member. It's free and easy to join, and you can even access member perks too. Just remember to sign in to get our best prices on Isle of Palms hotels. Another way to save is by booking your hotel and flights together on Expedia, where bundling can lead to significant savings.
How much is the nightly rate at a Isle of Palms hotel?
Hotel prices in Isle of Palms often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.

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